POSITION: Professor Derralynn Hughes is Clinical Director Haematology, Oncology and Palliative Care and Lead Cancer Physician at the Royal Free London NHS Foundation Trust and Professor of Experimental Haematology at the University College London, UK.
She has clinical responsibilities in the area of Haematology and Lysosomal Storage Disorders and is chair of the anaemia clinical practice group. She directs the research programme in the LSD unit research laboratory where interests include understanding the pathophysiology of phenotypic heterogeneity in Fabry Disease and bone related pathology in Gaucher disease and malignancy.
WORKING/RESEARCH FOCUS: Prof Hughes is Principle Investigator of a number of clinical trials examining the efficacy of Enzyme, Chaperone and gene therapies and other new agents in the treatment of Gaucher, Fabry, Pompe and MPS disorders. A particular interest relates to the clinical and biological effects of bone disease and malignancy in Gaucher disease. She is an author of over 150 papers in the area of macrophage biology and lysosomal Storage Disorders.